To meet Paris Agreement goals, Latin America can achieve net-zero emissions by 2050-’70, benefiting air quality and the economy. Countries have the power to define their contributions. Long-term strategies are crucial for climate goals, and 2025-2030 targets should align with net-zero by 2050-’70. Key transformations include electrification, mode shifting, and reducing fossil fuels. Alternative fuels like hydrogen are needed. Comprehensive policies are essential, including subsidy reductions and electrification mandates. International cooperation is vital where capacity gaps exist. Building consensus among stakeholders and reviewing policies for net-zero are immediate priorities.